The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10927406 B1

PDF
Full Text
Expired
Date of Patent:
Feb. 23, 2021

Filed:

Jun. 15, 2016
Applicant:

National University of Singapore, Singapore, SG;

Inventors:

Dieter Trau, Singapore, SG;

Wen-Tso Liu, Singapore, SG;

Kian Kok Johnson Ng, Singapore, SG;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6837 (2018.01); G06T 7/00 (2017.01); G06T 5/50 (2006.01); C40B 20/02 (2006.01); B01J 19/00 (2006.01); C40B 30/04 (2006.01); C04B 40/04 (2006.01); G01N 21/64 (2006.01); C12Q 1/6834 (2018.01); G06T 7/33 (2017.01); G01N 33/543 (2006.01); G01N 33/545 (2006.01); C40B 50/16 (2006.01); C40B 50/18 (2006.01); C12Q 1/6883 (2018.01); C40B 40/04 (2006.01); C40B 60/14 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6837 (2013.01); B01J 19/0046 (2013.01); C12Q 1/6834 (2013.01); C12Q 1/6883 (2013.01); C40B 20/02 (2013.01); C40B 30/04 (2013.01); C40B 40/04 (2013.01); G01N 21/6452 (2013.01); G01N 33/545 (2013.01); G01N 33/54313 (2013.01); G01N 33/54373 (2013.01); G06T 5/50 (2013.01); G06T 7/0008 (2013.01); G06T 7/33 (2017.01); B01J 2219/0054 (2013.01); B01J 2219/0074 (2013.01); B01J 2219/00317 (2013.01); B01J 2219/00459 (2013.01); B01J 2219/00466 (2013.01); B01J 2219/00648 (2013.01); B01J 2219/00659 (2013.01); B01J 2219/00677 (2013.01); B01J 2219/00702 (2013.01); B01J 2219/00722 (2013.01); C40B 50/16 (2013.01); C40B 50/18 (2013.01); C40B 60/14 (2013.01);
Abstract

A process for identifying one or more target analytes present in a sample includes contacting a microarray with the sample. The microarray has at least two microbead subpopulations with randomly distributed spatial positions, each of the subpopulations comprising microbeads having a known active agent capable of binding with a respective target analyte. After contacting the microarray with the sample, the spatial positions of the microbeads which have undergone a change that is indicative of a respective one of the active agents being bound to a corresponding one of the target analytes are determined. At least one of the microbead subpopulations which has undergone the change is identified by comparing the determined spatial positions to recorded spatial positions of the microbeads of the microbead subpopulations stored in an encoding/decoding data table. The target analytes are identified based on the known active agents belonging to the at least one identified microbead subpopulation.


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