The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 23, 2021

Filed:

Nov. 25, 2019
Applicant:

Bluebird Bio, Inc., Cambridge, MA (US);

Inventors:

Jordan Jarjour, Seattle, WA (US);

Kyle Havens, Seattle, WA (US);

Anne-Rachel Krostag, Lake Forest Park, WA (US);

Assignee:

bluebird bio, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/22 (2006.01); C12N 9/16 (2006.01); C12N 15/10 (2006.01); C12N 5/0783 (2010.01); C12N 9/10 (2006.01); C12N 15/90 (2006.01);
U.S. Cl.
CPC ...
C12N 15/102 (2013.01); C12N 5/0636 (2013.01); C12N 5/0646 (2013.01); C12N 9/10 (2013.01); C12N 15/907 (2013.01); C12N 2800/80 (2013.01);
Abstract

The present disclosure provides improved genome editing compositions and methods for editing a CBLB gene. The disclosure further provides genome edited cells for the prevention, treatment, or amelioration of at least one symptom of, a cancer, an infectious disease, an autoimmune disease, an inflammatory disease, or an immunodeficiency.


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