The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 23, 2021

Filed:

Jul. 14, 2017
Applicant:

Novozymes A/s, Bagsvaerd, DK;

Inventors:

Keiichi Ayabe, Chiba, JP;

Tomoko Matsui, Chiba, JP;

Aki Tomiki, Chiba, JP;

Yuma Kurakata, Chiba, JP;

Esben P. Friis, Herlev, DK;

Jens E. Nielsen, Bagsvaerd, DK;

Roland Alexander Pache, Valby, DK;

Assignee:

NOVOZYMES A/S, Bagsvaerd, DK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/58 (2006.01); C12P 7/06 (2006.01);
U.S. Cl.
CPC ...
C12N 9/58 (2013.01); C12P 7/06 (2013.01); C12Y 304/21 (2013.01);
Abstract

The present invention relates to protease variants, having improved properties compared to the parent protease, in particular variants of a serine protease belonging to family 53 derived from a strain of. The variants according to the invention have in particular increased thermo-stability, e.g., increased residual activity after 30 min at a temperature in the range from 55 to 60° C. and/or increased thermal denaturation temperature, compared to the parentprotease. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of using the variants.


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