The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 2021
Filed:
Jul. 29, 2018
Applicant:
Enlivex Therapeutics Ltd, Nes-Ziona, IL;
Inventors:
Dror Mevorach, Jerusalem, IL;
Inna Reiner, Jerusalem, IL;
Assignee:
ENLIVEX THERAPEUTICS LTD, Nes-Ziona, IL;
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/078 (2010.01); A61K 35/17 (2015.01); A61K 45/06 (2006.01); A61P 37/00 (2006.01); A61K 31/727 (2006.01); A61K 31/194 (2006.01); A61K 31/573 (2006.01); A61K 31/7004 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0634 (2013.01); A61K 31/194 (2013.01); A61K 31/573 (2013.01); A61K 31/7004 (2013.01); A61K 31/727 (2013.01); A61K 35/17 (2013.01); A61K 45/06 (2013.01); A61P 37/00 (2018.01);
Abstract
The present application provides pharmaceutical compositions comprising a population of mononuclear-enriched cells in an early-apoptotic state, methods for the production of said compositions and uses thereof in the treatment of diseases characterized by pathological immune responses. The pharmaceutical compositions may be used in treatment of conditions such as, but not limited to, graft versus host disease (GVHD) and autoimmune diseases including but not limited to inflammatory bowel disease, gout and arthritis.