The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 2021
Filed:
Aug. 26, 2019
Applicant:
Duke University, Durham, NC (US);
Inventors:
Timothy Haystead, Chapel Hill, NC (US);
Philip Floyd Hughes, Chapel Hill, NC (US);
Assignee:
Duke University, Durham, NC (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/404 (2006.01); A61K 31/416 (2006.01); C07D 209/04 (2006.01); C07D 231/56 (2006.01); C07D 473/34 (2006.01); C07D 413/12 (2006.01); C07D 473/24 (2006.01); C07D 487/04 (2006.01); C07D 493/10 (2006.01); C07D 231/54 (2006.01); C07D 405/14 (2006.01); G01N 33/569 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C07D 473/34 (2013.01); C07D 231/54 (2013.01); C07D 405/14 (2013.01); C07D 413/12 (2013.01); C07D 473/24 (2013.01); C07D 487/04 (2013.01); C07D 493/10 (2013.01); G01N 33/56988 (2013.01); G01N 33/574 (2013.01); G01N 33/57496 (2013.01); G01N 2333/47 (2013.01);
Abstract
Substituted indazoles linked to a substituted adenine with a polyethylene glycol moiety selectively bind to Hsp90. The compounds include detection moieties such as fluorophores and are useful in methods and kits for selective detection of Hsp90 in a sample.