The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 23, 2021

Filed:

Jul. 01, 2016
Applicants:

The Medical College of Wisconsin, Inc., Milwaukee, WI (US);

Johann Wolfgang Goethe-universitat Frankfurt, Frankfurt am Main, DE;

Inventors:

John David Imig, Pewaukee, WI (US);

Md. Abdul Hye Khan, Milwaukee, WI (US);

Eugen Proschak, Frankfurt am Main, DE;

Rene Blocher, Frankfurt am Main, DE;

Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 233/66 (2006.01); C07C 233/73 (2006.01); C07C 233/65 (2006.01); A61P 3/10 (2006.01); A61K 9/00 (2006.01); A61M 25/01 (2006.01); A61B 5/06 (2006.01); A61M 25/00 (2006.01); A61B 18/14 (2006.01); A61B 18/00 (2006.01); A61B 5/00 (2006.01); A61B 34/20 (2016.01);
U.S. Cl.
CPC ...
C07C 233/66 (2013.01); A61B 5/062 (2013.01); A61B 18/1492 (2013.01); A61K 9/0053 (2013.01); A61M 25/0012 (2013.01); A61M 25/0127 (2013.01); A61P 3/10 (2018.01); C07C 233/65 (2013.01); C07C 233/73 (2013.01); A61B 5/6852 (2013.01); A61B 2018/00029 (2013.01); A61B 2018/00577 (2013.01); A61B 2034/2051 (2016.02);
Abstract

N-benzylbenzamides that act as dual soluble soluble epoxide hydrolase (sEH)/peroxisome proliferator-activated receptor γ (PPARγ) modulators and are useful as medications in the treatment of Metabolic Syndrome (MetS) cluster diseases, including diabetes. Methods of making and using the same are further provided.


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