The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 23, 2021

Filed:

Nov. 10, 2016
Applicants:

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);

Sanford Research, Sioux Falls, SD (US);

Inventors:

Ira H. Pastan, Potomac, MD (US);

Tapan Bera, Frederick, MD (US);

Satoshi Nagata, Osaka, JP;

Tomoko Ise, Osaka, JP;

Yasuhiro Abe, Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 47/64 (2017.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6415 (2017.08); A61K 39/00 (2013.01); A61K 47/6425 (2017.08); C07K 16/2878 (2013.01); A61K 2039/505 (2013.01); C07K 2319/03 (2013.01);
Abstract

Polypeptides and proteins that specifically bind to and immunologically recognize B-Cell Maturation Antigen (BCMA) are disclosed. Chimeric antigen receptors (CARs), anti-BCMA binding moieties, nucleic acids, recombinant expression vectors, host cells, populations of cells, pharmaceutical compositions, and conjugates relating to the polypeptides and proteins are also disclosed. Methods of detecting the presence of cancer and methods of treating or preventing cancer are also disclosed.


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