The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 23, 2021

Filed:

Jul. 21, 2015
Applicants:

Japan As Represented BY Director General of National Institute of Infectious Diseases, Tokyo, JP;

Nippi, Incorporated, Tokyo, JP;

Inventors:

Shinji Saito, Tokyo, JP;

Tadaki Suzuki, Tokyo, JP;

Hideki Hasegawa, Tokyo, JP;

Akira Ainai, Tokyo, JP;

Kiyoko Goto, Tokyo, JP;

Tomonori Ueno, Kashiwa, JP;

Yuki Taga, Tokyo, JP;

Assignee:

Nippi, Incorporated, Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/18 (2006.01); C12N 15/09 (2006.01); C07K 16/06 (2006.01); C12N 15/01 (2006.01); C12N 15/10 (2006.01); C12N 15/66 (2006.01); C07K 16/10 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/395 (2013.01); C07K 16/065 (2013.01); C07K 16/18 (2013.01); C12N 15/01 (2013.01); C12N 15/09 (2013.01); C12N 15/1086 (2013.01); C12N 15/66 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 16/10 (2013.01);
Abstract

Provided are: a polymeric IgA-type recombinant antibody; a medicine containing this polymeric IgA-type recombinant antibody as an active ingredient; a method for producing this polymeric IgA type antibody, the method including the step of coexpressing an IgA-type antibody heavy-chain protein, an antibody light-chain protein, an antibody J-chain protein, and a secretory component protein within a single cell; and a method for improving the antigen-binding activity or neutralizing activity of this antibody, the method including the step of making an antibody into a polymeric IgA-type.


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