The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 23, 2021
Filed:
Dec. 03, 2019
Applicants:
Vor Biopharma, Inc, Cambridge, MA (US);
Puretech Management, Inc., Boston, MA (US);
Inventors:
Joseph Bolen, Boston, MA (US);
Aleksandar Filip Radovic-Moreno, Boston, MA (US);
John Lydeard, Sharon, MA (US);
Assignee:
VOR BIOPHARMA, INC, Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/28 (2015.01); A61P 35/02 (2006.01); A61K 35/17 (2015.01); A61K 39/395 (2006.01); C12N 15/90 (2006.01); A61K 38/17 (2006.01); C12N 5/0789 (2010.01); C12N 9/22 (2006.01); C12N 15/11 (2006.01); C07K 14/705 (2006.01); A61P 35/00 (2006.01); A61K 35/12 (2015.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/28 (2013.01); A61K 35/17 (2013.01); A61K 38/178 (2013.01); A61K 38/1774 (2013.01); A61K 39/3955 (2013.01); A61P 35/00 (2018.01); A61P 35/02 (2018.01); C07K 14/7056 (2013.01); C07K 14/70596 (2013.01); C12N 5/0647 (2013.01); C12N 9/22 (2013.01); C12N 15/11 (2013.01); C12N 15/907 (2013.01); A61K 2035/124 (2013.01); A61K 2039/505 (2013.01); C12N 2310/20 (2017.05); C12N 2510/00 (2013.01); C12N 2800/80 (2013.01);
Abstract
Genetically engineered hematopoietic cells such as hematopoietic stem cells having one or more genetically edited genes of lineage-specific cell-surface proteins and therapeutic uses thereof, either alone or in combination with immune therapy that targets the lineage-specific cell-surface proteins.