The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 23, 2021

Filed:

Mar. 01, 2019
Applicant:

Washington University, Saint Louis, MO (US);

Inventors:

Shin-ichiro Imai, Saint Louis, MO (US);

Rajendra Apte, Clayton, MO (US);

Assignee:

Washington University, St. Louis, MO (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/04 (2006.01); A61K 31/70 (2006.01); A61K 31/706 (2006.01); A61K 31/455 (2006.01); A61K 9/00 (2006.01); A61K 31/7064 (2006.01);
U.S. Cl.
CPC ...
A61K 31/706 (2013.01); A61K 9/0014 (2013.01); A61K 9/0048 (2013.01); A61K 9/0053 (2013.01); A61K 31/455 (2013.01); A61K 31/7064 (2013.01);
Abstract

Disclosed are methods and compositions related to methods of treating, ameliorating, mitigating, slowing, arresting, preventing or reversing various diseases and conditions, including age-related obesity, age-related increases in blood lipid levels, age-related decreases in insulin sensitivity, age-related decreases in memory function, and age-related changes in eye function such as macular degeneration. The methods comprise administering nicotinamide mononucleotide (NMN) to a subject. In some embodiments, the administration can be oral administration. Also disclosed are pharmaceutical compositions comprising NMN.


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