The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 16, 2021

Filed:

Jul. 10, 2019
Applicant:

Case Western Reserve University, Cleveland, OH (US);

Inventors:

Pallavi Tiwari, Wexford, PA (US);

Marwa Ismail, Louisville, KY (US);

Anant Madabhushi, Shaker Heights, OH (US);

Assignee:

Case Western Reserve University, Cleveland, OH (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G06T 7/33 (2017.01); G01R 33/56 (2006.01); G06F 17/18 (2006.01); G16H 20/40 (2018.01); G06T 7/10 (2017.01); G16H 20/10 (2018.01); G16H 30/40 (2018.01);
U.S. Cl.
CPC ...
G01R 33/56 (2013.01); G06F 17/18 (2013.01); G06T 7/10 (2017.01); G06T 7/337 (2017.01); G16H 20/10 (2018.01); G16H 20/40 (2018.01); G16H 30/40 (2018.01); G06T 2207/10088 (2013.01); G06T 2207/30016 (2013.01); G06T 2207/30096 (2013.01);
Abstract

Embodiments discussed herein facilitate generating a quantitative population atlas of tumor progression (TP) versus pseudo-progression (PsP) in Glioblastoma (GBM). A first set of embodiments discussed herein relates to generating a quantitative population atlas of TP versus PsP based on a plurality of multi-parametric (mpMRI) studies of a population of patients demonstrating GBM. A second set of embodiments discussed herein relates to computing a probability that a patient will experience PsP or TP based on a DICE analysis of a mapping of a diagnostic mpMRI study associated with the patient into the quantitative population atlas space.


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