The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 2021
Filed:
Jan. 15, 2016
Applicant:
Takeda Vaccines, Inc., Cambridge, MA (US);
Inventors:
Joel R. Haynes, Bozeman, MT (US);
Evelyn Benson, Bozeman, MT (US);
Assignee:
Takeda Vaccines, Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12Q 1/70 (2006.01); C12N 9/12 (2006.01); C12N 7/02 (2006.01); C12Q 1/6806 (2018.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/702 (2013.01); C12N 7/00 (2013.01); C12N 7/02 (2013.01); C12N 9/1276 (2013.01); C12Q 1/6806 (2013.01); C12Q 1/70 (2013.01); C12Q 1/701 (2013.01); C12Y 207/07049 (2013.01); C12Y 304/21062 (2013.01); C12N 2740/00011 (2013.01); C12N 2740/10023 (2013.01);
Abstract
The present invention relates to methods and kits for detecting in a sample the presence of a virus particle or a virus-like particle that has reverse transcriptase activity and methods for preparing a retroviral contaminant-free substance. An aspect of the present invention is a method for detecting the presence of a virus particle in a sample of a Virus-like Particle (VLP) drug substance comprising a step of performing PCR-based reverse transcriptase (PBRT) on a sample of the VLP drug substance that has been treated with a protease.