The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 2021
Filed:
Nov. 14, 2019
Applicant:
Invista North America S.á.r.l., Wilmington, DE (US);
Inventors:
Alex Van Eck Conradie, Eaglescliffe, GB;
Adriana Leonora Botes, Rosedale East, GB;
Assignee:
INV Nylon Chemicals Americas, LLC, Wilmington, DE (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/52 (2006.01); C12P 13/00 (2006.01); C12P 7/42 (2006.01); C12P 7/44 (2006.01); C12P 11/00 (2006.01); C12P 19/32 (2006.01); C12P 7/26 (2006.01); C12P 7/18 (2006.01); C08G 69/28 (2006.01); C12N 9/10 (2006.01); C12P 7/04 (2006.01);
U.S. Cl.
CPC ...
C12P 13/001 (2013.01); C08G 69/28 (2013.01); C12N 9/1029 (2013.01); C12N 9/1096 (2013.01); C12N 15/52 (2013.01); C12P 7/04 (2013.01); C12P 7/18 (2013.01); C12P 7/26 (2013.01); C12P 7/42 (2013.01); C12P 7/44 (2013.01); C12P 11/00 (2013.01); C12P 13/00 (2013.01); C12P 13/005 (2013.01); C12P 19/32 (2013.01); C12Y 203/01016 (2013.01); C12Y 203/01174 (2013.01); C12Y 206/01002 (2013.01);
Abstract
This document describes biochemical pathways for biosynthesizing a 3-oxo-7-hydroxyheptanoyl-CoA intermediate using a β-ketothiolase, and enzymatically converting 3-oxo-7-hydroxyheptanoyl-CoA to 7-hydroxyheptanoic acid. —7-hydroxyheptanoic acid can be further enzymatically converted to pimelic acid, 7-aminoheptanoic acid, heptamethylenediamine or 1,7-heptanediol. This document also describes recombinant hosts producing 7-hydroxyheptanoic acid as well as pimelic acid, 7-aminoheptanoic acid, heptamethylenediamine and 1,7-heptanediol.