The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 2021
Filed:
Feb. 26, 2016
Salk Institute for Biological Studies, La Jolla, CA (US);
Ronald Evans, La Jolla, CA (US);
Michael Downes, La Jolla, CA (US);
Yasuyuki Kida, La Jolla, CA (US);
Teruhisa Kawamura, La Jolla, CA (US);
Zong Wei, La Jolla, CA (US);
Ruth T. Yu, La Jolla, CA (US);
Annette R. Atkins, La Jolla, CA (US);
SALK INSTITUTE FOR BIOLOGICAL STUDIES, La Jolla, CA (US);
Abstract
The invention generally features compositions comprising induced pluripotent stem cell progenitors (also termed reprogramming progenitor cells) and methods of isolating such cells. The invention also provides compositions comprising induced pluripotent stem cells (iPSCs) derived from such progenitor cells. Induced pluripotent stem cell progenitors generate iPSCs at high efficiency. In particular embodiments the invention is predicated upon increased expression of an estrogen related receptor and changes in the oxidative and glycolytic pathways.