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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10919977 B1

PDFFull Text
Date of Patent:
Feb. 16, 2021

Filed:

Dec. 19, 2015

Bispecific tetravalent antibodies and methods of making and using thereof

Applicant:

Systimmune, Inc., Bellevue, WA (US);

Inventors:

Zeren Gao, Bellevue, WA (US);

Phil Tan, Bellevue, WA (US);

Brian R. Kovacevich, Bellevue, WA (US);

Blair R. Renshaw, Bellevue, WA (US);

Jeffrey B. Adamo, Bellevue, WA (US);

Nga Sze Amanda Mak, Bellevue, WA (US);

Shi Zhuo, Chengdu, CN;

Lan Chen, Chengdu, CN;

Yi Zhu, Chengdu, CN;

Assignees:

SYSTIMMUNE, INC., Bellevue, WA (US);

Sichuan Baili Pharmaceutical Co. Ltd., Chengdu, CN;

Attorneys:

Zhihua Han

Wen IP LLC

Primary Examiner:

Nelson B Moseley, Ii

Int. Cl.
CPC ...
C07K 16/30 (2006.01); C07K 16/32 (2006.01); A61K 47/68 (2017.01); C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); C07K 16/46 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/3015 (2013.01); A61K 39/3955 (2013.01); A61K 39/39558 (2013.01); A61K 45/06 (2013.01); A61K 47/6803 (2017.08); A61K 47/6849 (2017.08); A61K 47/6851 (2017.08); C07K 16/2863 (2013.01); C07K 16/32 (2013.01); C07K 16/468 (2013.01); A61K 2039/505 (2013.01); A61K 2039/5152 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/35 (2013.01); C07K 2317/622 (2013.01); C07K 2317/64 (2013.01); C07K 2317/73 (2013.01); C07K 2317/732 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract

A bispecific tetravalent antibody comprising an IgG having a pair of heavy chains and a pair of light chains, and two scFv components being connected to either C or N terminals of the heavy or light chains. The bispecific tetravalent antibody may have a binding specificity for two different members of EGFR family.

Find Patent Forward Citations

Gao, Zeren. (2021). Bispecific tetravalent antibodies and methods of making and using thereof (U.S. Patent No. 10919977). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10919977

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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