The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 2021
Filed:
Jun. 13, 2017
Applicants:
Albert-ludwigs-universität Freiburg, Freiburg, DE;
Baker Idi Heart & Diabetes Institute Holdings Ltd., Melbourne, AU;
Inventors:
Assignees:
ALBERT-LUDWIGS-UNIVERSITÄTFREIBURG, Freiburg, DE;
BAKER IDI HEART & DIABETES INSTITUTE HOLDINGS LTD., Melbourne, AU;
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C07K 16/46 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2845 (2013.01); A61K 2039/505 (2013.01); C07K 2317/32 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/55 (2013.01); C07K 2317/70 (2013.01); C07K 2317/76 (2013.01);
Abstract
The present invention provides an isolated monoclonal antibody or an antigen-binding portion thereof which a) binds to Mac-1, b) specifically inhibits the interaction of CD40L with activated Mac-1 and c) does not induce integrin outside-in signaling.