The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 2021
Filed:
Jan. 29, 2018
Applicant:
Boehringer Ingelheim Vetmedica Gmbh, Ingelheim am Rhein, DE;
Inventors:
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/435 (2006.01); C07K 14/415 (2006.01); C07K 14/005 (2006.01); A61K 39/35 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/43563 (2013.01); A61K 39/35 (2013.01); C07K 14/005 (2013.01); C07K 14/415 (2013.01); A61K 2039/552 (2013.01); A61K 2039/55505 (2013.01); A61K 2039/60 (2013.01); C07K 2319/00 (2013.01); C07K 2319/01 (2013.01); C07K 2319/06 (2013.01); C07K 2319/10 (2013.01); C07K 2319/21 (2013.01); C07K 2319/40 (2013.01);
Abstract
The present invention relates to (isolated) recombinant proteins, also referred to as improved MAT (iMAT) molecules, comprising at least one translocation module, at least one targeting module and at least one antigen module, wherein at least one cysteine residue is substituted with a different amino acid residue. Such iMAT molecules are useful specifically as vaccines, e.g., for therapy and/or prevention of allergies and/or infectious diseases and/or prevention of transmission of infectious diseases in equines. The present invention further relates to nucleic acids encoding such iMAT molecules, corresponding vectors and primary cells or cell lines.