The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 2021
Filed:
Sep. 22, 2017
Cancer Research Technology Limited, London, GB;
Emma L. Carswell, Cambridge, GB;
Mark David Charles, Cambridge, GB;
Anne Cochi, Cambridge, GB;
Benjamin J. Dugan, West Chester, PA (US);
Chukuemeka Tennyson Ekwuru, Cambridge, GB;
Fred Elustondo, Cambridge, GB;
Katherine M. Fowler, Cambridge, GB;
Frederic Georges Marie Leroux, Cambridge, GB;
Nathaniel J. T. Monck, Cambridge, GB;
Gregory R. Ott, West Chester, PA (US);
Jonathan R. Roffey, Cambridge, GB;
Gurwinder Sidhu, Cambridge, GB;
Neil Tremayne, Cambridge, GB;
Cancer Research Technology Limited, London, GB;
Abstract
The present invention relates to compounds of formula (I), and salts and solvates thereof, that function as inhibitors of cell division cycle 7 (Cdc7) kinase enzyme activity: wherein X, R, R, and n are each as defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of proliferative disorders, such as cancer, as well as other diseases or conditions in which Cdc7 kinase activity is implicated.