The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 2021
Filed:
Apr. 27, 2018
Applicant:
Unichem Laboratories Ltd, Maharashtra, IN;
Inventors:
Dhananjay G. Sathe, Maharashtra, IN;
Arijit Das, Goa, IN;
Bhavesh B. Patel, Gujarat, IN;
Dipak Subhash Patil, Maharashtra, IN;
Ashok Govind Matale, Maharashtra, IN;
Eknath Kamalakar Kshirsagar, Maharashtra, IN;
Assignee:
UNICHEM LABORATORIES LTD, Maharashtra, IN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/48 (2006.01);
U.S. Cl.
CPC ...
C07D 209/48 (2013.01);
Abstract
An alternative and improved process for the preparation of Apremilast (Formula I) and Apremilast form B or a pharmaceutically acceptable salt thereof is provided. The novel process includes hydrogenation in acetone, Cyclization and acetylation followed by condensation in methyl isobutyl ketone (MIBK) and acetic acid mixture in specific volume ratios.