The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 16, 2021

Filed:

Jan. 27, 2017
Applicants:

Inserm (Institut National DE LA Santé ET DE LA Recherche Médicale), Paris, FR;

Université Paul Sabatier Toulouse Iii, Toulouse, FR;

Centre Hospitalier Universitaire DE Toulouse, Toulouse, FR;

Inventors:

Thierry Levade, Toulouse, FR;

Bruno Segui, Toulouse, FR;

Nicolas Meyer, Toulouse, FR;

Céline Colacios Viatgé, Toulouse, FR;

Nathalie Andrieu-Abadie, Toulouse, FR;

Florie Bertrand, Toulouse, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); A61K 47/68 (2017.01); C07K 16/24 (2006.01); C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 47/6845 (2017.08); A61K 39/39558 (2013.01); A61P 35/00 (2018.01); C07K 16/241 (2013.01); C07K 16/2818 (2013.01); C07K 16/2878 (2013.01); A61K 45/06 (2013.01); A61K 2039/507 (2013.01); A61K 2039/57 (2013.01); C07K 2317/31 (2013.01);
Abstract

The present invention relates to methods and pharmaceutical composition for the treatment of cancer. In particular, the present invention relates to a method for enhancing the potency of an immune checkpoint inhibitor administered to a subject as part of a treatment regimen for cancer, the method comprising: administering a pharmaceutically effective amount of a TNFα blocking agent to a subject in combination with the immune checkpoint inhibitor.


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