The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 2021
Filed:
Mar. 05, 2019
Massachusetts Institute of Technology, Cambridge, MA (US);
The Board of Trustees of the University of Illinois, Urbana, IL (US);
Mohammad Movassaghi, Lincoln, MA (US);
Justin Kim, Sunland, CA (US);
Paul Hergenrother, Champaign, IL (US);
Karen Morrison, West Sacramento, CA (US);
Nicolas Boyer, Somerville, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
The Board of Trustees of the University of Illinois, Urbana, IL (US);
Abstract
The synthesis of various pyrazino[1',2′:1,5]pyrrolo[2,3-B]-indole-1,4-dione analogs has been successfully implemented in the present application. From these efforts, compounds having the structure of Formula I-a or Formula I-b: or a pharmaceutically acceptable salt, tautomer, or stereoisomer thereof, are provided herein. These biologically active derivatives have been used to effectively treat various diseases including cancer.