The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 16, 2021

Filed:

Oct. 21, 2014
Applicant:

Oxsonics Limited, Oxford, GB;

Inventors:

Steven Mo, Oxford, GB;

Robert Crispin Carlisle, Oxford, GB;

Leonard W. Seymour, Oxford, GB;

Constantin-Cassios Coussios, Oxford, GB;

Assignee:

Oxsonics Limited, Oxford, GB;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); A61K 41/00 (2020.01); A61K 47/69 (2017.01); A61K 47/60 (2017.01); A61K 33/24 (2019.01); A61M 37/00 (2006.01);
U.S. Cl.
CPC ...
A61K 41/0047 (2013.01); A61K 33/24 (2013.01); A61K 41/0028 (2013.01); A61K 47/60 (2017.08); A61K 47/6923 (2017.08); A61K 47/6929 (2017.08); A61M 37/0092 (2013.01); A61M 2037/0007 (2013.01);
Abstract

The invention disclosed herein relates to a method of cavitation-induced delivery of a therapeutic or diagnostic agent to a human or animal subject. In particular the invention provides an agent for use in a method of diagnosis or treatment of a human or animal subject, the method comprising exposing the subject to ultrasound, wherein the agent comprises a therapeutic or diagnostic component which is covalently bound to a dense component, the dense component having a density greater than that of the therapeutic or diagnostic component, and wherein either the dense component is a cavitation initiator or the method comprises administering to the subject a further agent which is a cavitation initiator. Binding of the dense component enhances cavitation-induced transport of the therapeutic or diagnostic component.


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