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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10918710 B1

PDFFull Text
Expired
Date of Patent:
Feb. 16, 2021

Filed:

Nov. 20, 2017

Temperature-sensitive attenuated fmdv strains, construction method and application thereof

Applicant:

Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, CN;

Inventors:

Li Yu, Harbin, CN;

Decheng Yang, Harbin, CN;

Haiwei Wang, Harbin, CN;

Guohui Zhou, Harbin, CN;

Assignee:

HARBIN VETERINARY RESEARCH INSTITUTE. CHINESE ACADEMY OF AGRICULTURAL SCIENCES, Harbin, CN;

Attorney:

Bayramoglu Law Offices LLC

Primary Examiner:

Shanon A Foley

Int. Cl.
CPC ...
A61K 39/135 (2006.01); A61P 31/14 (2006.01); C12N 15/113 (2010.01); C12N 7/00 (2006.01); C12N 7/04 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/135 (2013.01); A61P 31/14 (2018.01); C12N 7/00 (2013.01); C12N 7/04 (2013.01); C12N 15/113 (2013.01); A61K 2039/53 (2013.01); A61K 2039/552 (2013.01);
Abstract

A temperature-sensitive attenuated FMDV strain, construction method and applications thereof. The construction method of the temperature-sensitive attenuated FMDV strain is as follows. Mutating a cytosine on K region loop of IRES domain 4 of an FMDV genome to a guanine or an adenine to obtain the temperature-sensitive attenuated FMDV strain, or replacing a K region of IRES domain 4 of an FMDV genome with a K region of IRES domain 4 of a bovine rhinovirus genome to obtain the temperature-sensitive attenuated FMDV strain.

Find Patent Forward Citations

Yu, Li. (2021). Temperature-sensitive attenuated fmdv strains, construction method and application thereof (U.S. Patent No. 10918710). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10918710

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