The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 2021
Filed:
Jan. 03, 2019
The Secretary, Department of Atomic Energy, Mumbai, IN;
Deepak Sharma, Mumbai, IN;
Santosh Kumar Sandur, Mumbai, IN;
Maikho Thoh, Mumbai, IN;
Raghavendra Shridhar Patwardhan, Mumbai, IN;
Dharmendra K. Maurya, Mumbai, IN;
Rahul Checker, Mumbai, IN;
Vikram P. Gota, Navi Mumbai, IN;
Jayakumar Sundarraj, Mumbai, IN;
Haldhar Dev Sarma, Mumbai, IN;
Subrata Chattopadhyay, Mumbai, IN;
THE SECRETARY, DEPARTMENT OF ATOMIC ENERGY, Maharastra, IN;
Abstract
A method of treatment of disease condition resulting from deficiency of hematopoietic stem and progenitor cells and/or epidermal stem cells in skin comprising: administering to the subject suffering from said disease conditions, an effective amount of Jack bean lectin or a pharmaceutically acceptable salt thereof for increasing the abundance of hematopoietic stem cells and progenitor cells in bone marrow and/or epidermal stem cells in skin in vivo. Method of treating said conditions in a subject involves administering a single injection of lectin in a dose range of 0.5-2.0 mg/kg body weight to mouse leading to 2.815 to 3.55 fold increase in the abundance of epidermal stem cells in skin and a dose range of 8.0-10.0 mg/Kg body weight to a mouse leading to 2.36 to 6.67-fold increase in the abundance of hematopoietic stem and progenitor cells in bone marrow.