The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 16, 2021
Filed:
Oct. 10, 2017
Applicants:
Deutsches Zentrum Für Neurodegenerative Erkrankungen E. V. (Dzne), Bonn, DE;
Klinikum Rechts Der Isar Der Technischen Universität München, Munich, DE;
Inventors:
Assignees:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4375 (2006.01); A61P 25/28 (2006.01); A61K 31/519 (2006.01); C12N 15/113 (2010.01); A61K 31/713 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4375 (2013.01); A61K 31/519 (2013.01); A61K 31/713 (2013.01); A61P 25/28 (2018.01); C12N 15/1137 (2013.01); C12Y 301/04017 (2013.01); C12N 2310/14 (2013.01);
Abstract
A modulator of PDE1A and/or PDE1C can be used as a medicament, in particular in the prevention or treatment of synucleinopathies, such as multiple system atrophy, dementia with Lewy bodies, Parkinson's disease, pure autonomic failure, rapid eye movement sleep behavior disorder, inherited synucleinopathies caused by mutations or multiplications of the SNCA gene, or synucleinopathies caused by mutations in other genes including, but not limited to, GBA, LRRK2 and PARK2.