The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 16, 2021

Filed:

Jun. 12, 2020
Applicant:

Geistlich Pharma Ag, Wolhusen, CH;

Inventors:

Daniel Suppiger, Rotkreuz, CH;

Paul Buxton, Lucerne, CH;

Nino Kurz, Langnau im Emmental, CH;

Assignee:

Geistlich Pharma AG, Wolhusen, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 33/06 (2006.01); A61M 5/20 (2006.01); A61K 31/375 (2006.01); A61K 47/42 (2017.01);
U.S. Cl.
CPC ...
A61K 9/0024 (2013.01); A61K 31/375 (2013.01); A61K 33/06 (2013.01); A61K 47/42 (2013.01); A61M 5/2066 (2013.01);
Abstract

An injectable aqueous implant formulation, and processes for making and using the formulation, wherein the injectable aqueous implant formulation has been sterilized by gamma-ray or X-ray-irradiation and can be extruded through a tapering system and an 18 gauge (0.838 mm inner diameter) 25.4 mm long cannula with a force not exceeding 60 N, which comprises 25-45 w/w % of a mixture of nanocrystalline hydroxyapatite particles derived from natural bone having a size of 50 to 200 μm as determined by sieving and fragments of naturally crosslinked fibrous collagen material that pass through a 0.5 mm sieve, whereby the w/w ratio of nanocrystalline hydroxyapatite to collagen is from 1.8 to 4.5, which contains at least 0.05% (w/w) ascorbic acid.


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