The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 09, 2021
Filed:
Jun. 04, 2020
Applicant:
King Saud University, Riyadh, SA;
Inventor:
Md. Ashrafuzzaman, Riyadh, SA;
Assignee:
KING SAUD UNIVERSITY, Riyadh, SA;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/115 (2010.01); G16B 5/20 (2019.01);
U.S. Cl.
CPC ...
G16B 5/20 (2019.02); C12N 15/115 (2013.01); C12N 2310/16 (2013.01); C12N 2330/30 (2013.01);
Abstract
A method of designing aptamers includes building an aptamer by a seed-and-grow method optimizing screened coulomb interactions (SCI) and selecting aptamer length based on an aptamer target biological environment. Aptamers designed according to the method may comprise any DNA or RNA nucleotides. In particular, for example, aptamers may be designed according to the method to target lipids that may be found in membranes, such as liposomes or micelles. The lipids may be phosphatidylserine (PS) or phosphatidylcholine (PC).