The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 09, 2021
Filed:
Feb. 16, 2016
Universidade DE Santiago DE Compostela, A Coruña, ES;
Servizo Galego DE Saude (Sergas), A Coruña, ES;
María Isabel Lema Gesto, A Coruña, ES;
José Antonio Castillo Sánchez, A Coruña, ES;
Tomás Sobrino Moreiras, A Coruña, ES;
Francisco Campos Perez, A Coruña, ES;
UNIVERSIDADE DE SANTIAGO DE COMPOSTELA, A Coruña, ES;
SERVIZO GALEGO DE SAUDE (SERGAS), A Coruña, ES;
Abstract
The invention relates to the field of the diagnosis and prognosis methods of molecular pathologies. In particular, the invention relates to methods for determining the diagnosis of an ectatic disease of the cornea in a subject, for determining the risk of developing an ectatic disease of the cornea in a subject, for determining the clinical outcome of a subject suffering from an ectatic disease of the cornea and for selecting a subject to be treated with a therapy for an ectatic disease of the cornea based on the determination of the expression levels of TLR2 and/or TLR4 markers. The invention also relates to the use of the TLR2 and/or TLR4 as diagnosis and prognosis markers for an ectatic disease of the cornea.