The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 09, 2021
Filed:
Nov. 12, 2015
Applicant:
Lek Pharmaceuticals D.d., Ljubljana, SI;
Inventors:
Uro{hacek over (s)} Jamnikar, Menges, SI;
Marjanca Blas, Menges, SI;
Kristina Gruden, Ljubljana, SI;
Assignee:
Lek Pharmaceuticals d.d., Ljubljana, SI;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6888 (2018.01); C12N 15/67 (2006.01); C07K 16/00 (2006.01); C12N 5/071 (2010.01); C12P 21/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6888 (2013.01); C07K 16/00 (2013.01); C12N 5/0682 (2013.01); C12N 15/67 (2013.01); C12P 21/00 (2013.01); C07K 2317/14 (2013.01); C07K 2317/51 (2013.01); C07K 2317/515 (2013.01); C12N 2510/02 (2013.01); C12Q 2600/158 (2013.01);
Abstract
The present invention relates in general to the field of recombinant protein expression. In particular, the present invention relates to a method for selecting a suitable candidate cell clone for recombinant protein expression and to a host cell for recombinant protein expression, the host cell exhibiting artificially modified gene expression of at least one gene selected from the group consisting of: Fkbp10, ZdhhC6, Myrip, Actc1, AC124993.19, Runx2, AC158560.4, PlekhB1, Rps6KA2, Sept1, Sprr2k, and Flt1.