The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 09, 2021

Filed:

Mar. 27, 2018
Applicant:

Mayo Foundation for Medical Education and Research, Rochester, MN (US);

Inventors:

Stephen James Russell, Rochester, MN (US);

Elizabeth J. Kelly, Rochester, MN (US);

Elizabeth M. Hadac, Oronoco, MN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/005 (2006.01); A61K 35/768 (2015.01); C12N 7/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/005 (2013.01); A61K 35/768 (2013.01); C12N 7/00 (2013.01); C12N 2770/32311 (2013.01); C12N 2770/32332 (2013.01); C12N 2770/32611 (2013.01); C12N 2770/32632 (2013.01); C12N 2840/102 (2013.01); Y02A 50/30 (2018.01);
Abstract

This document provides methods and materials related to the use of nucleic acid coding for viruses to reduce the number of viable cancer cells within a mammal. For example, methods for using infectious nucleic acid to treat cancer, engineered viral nucleic acid, methods for making engineered viral nucleic acid, methods for identifying infectious nucleic acid for treating cancer, methods and materials for controlling virus-mediated cell lysis, and methods and materials for assessing the control of virus-mediated cell lysis are provided.


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