The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 09, 2021
Filed:
May. 14, 2020
Applicant:
Vision Global Holdings Limited, Hong Kong, CN;
Inventors:
Sui-Yi Kwok, Hong Kong, CN;
Norman Fung-Man Wai, Vancouver, CA;
Man-Kin Wong, Hong Kong, CN;
Benjamin Chi-Yin Wai, Vancouver, CA;
Assignee:
Vision Global Holdings Limited, Hong Kong, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 5/12 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 5/12 (2013.01); A61K 38/00 (2013.01);
Abstract
Provided herein are mertansine polypeptide conjugates useful in the treatment of cancer, pharmaceutical compositions comprising the same, and methods of use and preparation thereof. The methods provided herein are highly N-terminal selective and are capable of yielding N-terminal mertansine conjugated polypeptides with site selectivity of 99% or greater.