The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 09, 2021

Filed:

May. 23, 2019
Applicant:

Genentech, Inc., South San Francisco, CA (US);

Inventors:

Huifen Chen, South San Francisco, CA (US);

Daniel Shore, South San Francisco, CA (US);

Elisia Villemure, South San Francisco, CA (US);

Matthew Volgraf, South San Francisco, CA (US);

Baihua Hu, Beijing, CN;

Aijun Lu, Beijing, CN;

Andrew Cridland, Harlow, GB;

Stuart Ward, Harlow, GB;

Francis Beaumier, Montreal, CA;

Martin Dery, Montreal, CA;

Robin Larouche-Gauthier, Montreal, CA;

Assignee:

Genentech, Inc., South San Francisco, CA (US);

Attorney:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); C07D 473/30 (2006.01); C07D 471/04 (2006.01); C07D 513/04 (2006.01); A61K 31/519 (2006.01); A61P 11/06 (2006.01); C07D 498/04 (2006.01);
U.S. Cl.
CPC ...
C07D 473/30 (2013.01); A61K 31/519 (2013.01); A61P 11/06 (2018.01); C07D 471/04 (2013.01); C07D 487/04 (2013.01); C07D 498/04 (2013.01); C07D 513/04 (2013.01);
Abstract

The invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as respiratory disorders or pain.


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