The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 09, 2021

Filed:

Feb. 12, 2018
Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Junqing Guo, Princeton, NJ (US);

Amy C. Hart, Ewing, NJ (US);

John E. Macor, Washington Crossing, PA (US);

Michael E. Mertzman, New Hope, PA (US);

William J. Pitts, Newtown, PA (US);

Steven H. Spergel, Warrington, PA (US);

Scott Hunter Watterson, Pennington, NJ (US);

Murugaiah Andappan Murugaiah Subbaiah, Tamil Radu, IN;

Jie Chen, Cambridge, MA (US);

Carolyn Diane Dzierba, Middletown, CT (US);

Guanglin Luo, Newtown, PA (US);

Jianliang Shi, Furlong, PA (US);

Sing-Yuen Sit, Meriden, CT (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61P 29/00 (2006.01); A61P 19/02 (2006.01); A61P 17/06 (2006.01); A61P 1/00 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01);
Abstract

Compounds having formula (I) (IX), and enantiomers, and diastereomers, stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, are useful as kinase modulators, including RIPK1 modulation. All the variables are as defined herein: (I), (II), (III), (IV), (V), (VI), (VII), (VIII), (IX).


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