The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 09, 2021
Filed:
Dec. 14, 2016
Applicant:
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Inventors:
Assignees:
Alectos Therapeutics Inc., Burnaby, CA;
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/454 (2006.01); C07D 417/06 (2006.01); C07D 417/14 (2006.01); C07D 409/06 (2006.01);
U.S. Cl.
CPC ...
C07D 417/06 (2013.01); C07D 409/06 (2013.01); C07D 417/14 (2013.01);
Abstract
The present invention is directed to thiazolyl piperidine compounds of the general structural formula I: which are inhibitors of O-GlcNAcase. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which O-GlcNAcase is involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which O-GlcNAcase is involved.