The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 09, 2021
Filed:
Feb. 22, 2018
The University of Tokyo, Bunkyo-ku, JP;
National University Corporation Tokyo Medical and Dental University, Bunkyo-ku, JP;
Kazunori Kataoka, Tokyo, JP;
Yasutaka Anraku, Tokyo, JP;
Nobuhiro Nishiyama, Tokyo, JP;
Kanjiro Miyata, Tokyo, JP;
Takehiko Ishii, Tokyo, JP;
Yu Matsumoto, Tokyo, JP;
Yu Fukusato, Tokyo, JP;
Akihiro Mizoguchi, Tokyo, JP;
Takanori Yokota, Tokyo, JP;
Hiroya Kuwahara, Tokyo, JP;
Kazutaka Nishina, Tokyo, JP;
Hidehiro Mizusawa, Tokyo, JP;
THE UNIVERSITY OF TOKYO, Bunkyo-ku, JP;
NATIONAL UNIVERSITY CORPORATION TOKYO MEDICAL AND DENTAL UNIVERSITY, Bunkyo-ku, JP;
Abstract
The present invention provides a vesicle, a conjugate, a composition comprising the vesicle or the conjugate, for use in delivering a drug to the brain, and a method for administering the same. The composition of the present invention is a composition for administration to a subject according to a dosing regimen, comprising a carrier for drug delivery, wherein the dosing regimen comprises administering the composition to a subject who has been fasted or caused to have hypoglycemia and inducing an increase in blood glucose level in the subject, and the carrier is modified at the outer surface thereof with a GLUT1 ligand.