The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 09, 2021

Filed:

Jul. 17, 2019
Applicant:

Signum Biosciences, Inc., Monmouth Junction, NJ (US);

Inventors:

Kristen Huber, Monmouth Junction, NJ (US);

Michael Voronkov, Monmouth Junction, NJ (US);

Jose Fernandez, Monmouth Junction, NJ (US);

Karl Rouzard, Monmouth Junction, NJ (US);

Eduardo Perez, Monmouth Junction, NJ (US);

Maxwell Stock, Monmouth Junction, NJ (US);

Jeffry Stock, Monmouth Junction, NJ (US);

Assignee:

Signum Biosciences, Inc., Monmouth Junction, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 8/97 (2017.01); A61K 36/9066 (2006.01); A61K 36/77 (2006.01); A61K 36/87 (2006.01); A61K 36/33 (2006.01); A61K 36/73 (2006.01); A61K 45/06 (2006.01); A61K 9/00 (2006.01); A61K 36/14 (2006.01); A61K 36/185 (2006.01); A61K 36/23 (2006.01); A61K 36/235 (2006.01); A61K 36/28 (2006.01); A61K 36/31 (2006.01); A61K 36/45 (2006.01); A61K 36/52 (2006.01); A61K 36/54 (2006.01); A61K 36/575 (2006.01); A61K 36/71 (2006.01); A61K 36/736 (2006.01); A61K 36/79 (2006.01); A61Q 19/08 (2006.01);
U.S. Cl.
CPC ...
A61K 36/9066 (2013.01); A61K 8/97 (2013.01); A61K 9/0014 (2013.01); A61K 9/0053 (2013.01); A61K 36/14 (2013.01); A61K 36/185 (2013.01); A61K 36/23 (2013.01); A61K 36/235 (2013.01); A61K 36/28 (2013.01); A61K 36/31 (2013.01); A61K 36/33 (2013.01); A61K 36/45 (2013.01); A61K 36/52 (2013.01); A61K 36/54 (2013.01); A61K 36/575 (2013.01); A61K 36/71 (2013.01); A61K 36/73 (2013.01); A61K 36/736 (2013.01); A61K 36/77 (2013.01); A61K 36/79 (2013.01); A61K 36/87 (2013.01); A61K 45/06 (2013.01); A61Q 19/08 (2013.01); A61K 2236/00 (2013.01); A61K 2236/31 (2013.01); A61K 2236/33 (2013.01); A61K 2236/331 (2013.01); A61K 2236/39 (2013.01); A61K 2236/51 (2013.01); A61K 2236/53 (2013.01); A61K 2800/5922 (2013.01); A61K 2800/782 (2013.01); A61K 2800/805 (2013.01); A61K 2800/92 (2013.01);
Abstract

Method of preparing a botanical extract that includes contacting a raw botanical with a solvent having a dielectric constant ranging from about 2.3 to about 25 and allowing the mixture to reside for a sufficient time to obtain a crude extract; filtering out remaining raw botanical and evaporating the solvent from the crude extract under reduced pressure to obtain a dried crude extract; washing the dried crude extract with a polar solvent having a dielectric constant of no less than 30, heating the resulting mixture, and allowing to cool to ambient; collecting a filtrate from the above cooled mixture; washing the collected filtrate with a non-polar solvent having a dielectric constant of no more than 2.0; and filtering and drying the mixture to obtain the botanical extract.


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