The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 09, 2021

Filed:

Feb. 28, 2020
Applicant:

First Wave Bio, Inc., Ann Arbor, MI (US);

Inventors:

Gary D. Glick, Ann Arbor, MI (US);

Luigi Franchi, Ann Arbor, MI (US);

Assignee:

First Wave Bio, Inc., Ann Arbor, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/167 (2006.01); A61K 9/00 (2006.01); A61K 45/06 (2006.01); A61K 9/10 (2006.01); A61K 47/32 (2006.01); A61K 47/38 (2006.01); A61K 9/16 (2006.01);
U.S. Cl.
CPC ...
A61K 31/167 (2013.01); A61K 9/0031 (2013.01); A61K 9/10 (2013.01); A61K 45/06 (2013.01); A61K 9/1635 (2013.01); A61K 47/32 (2013.01); A61K 47/38 (2013.01);
Abstract

This disclosure features chemical entities (e.g., a compound exhibiting activity as a mitochondrial uncoupling agent or a pharmaceutically acceptable salt and/or hydrate and/or cocrystal thereof, e.g., a compound, such as niclosamide or a pharmaceutically acceptable salt and/or hydrate and/or cocrystal thereof, e.g., a compound, such as a niclosamide analog, or a pharmaceutically acceptable salt and/or hydrate and/or cocrystal thereof) that are useful, e.g., for treating one or more symptoms of a pathology characterized by an abnormal inflammatory response (e.g., inflammatory bowel diseases) in a subject (e.g., a human). This disclosure also features compositions as well as other methods of using and making the same.


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