The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 02, 2021

Filed:

Nov. 22, 2017
Applicant:

New York University, New York, NY (US);

Inventors:

Stewart Russell, New York, NY (US);

Edward A. Fisher, Scarsdale, NY (US);

Youssef Zaim Wadghiri, New York, NY (US);

Ryan Casey, New York, NY (US);

Assignee:

New York University, New York, NY (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/20 (2019.01); G01N 21/64 (2006.01); G01N 21/77 (2006.01); G01N 21/55 (2014.01); G01N 24/08 (2006.01); A61K 49/00 (2006.01); A61K 49/10 (2006.01);
U.S. Cl.
CPC ...
G01N 33/20 (2013.01); A61K 49/0021 (2013.01); A61K 49/105 (2013.01); G01N 21/55 (2013.01); G01N 21/6428 (2013.01); G01N 21/77 (2013.01); G01N 24/08 (2013.01); G01N 2021/7786 (2013.01);
Abstract

The invention provides methods and kits for detecting the presence of, the amount of, or the concentration of a substantially non-emitting metal in a sample by a) providing a sensitizer to a chelator of the substantially non-emitting metal thereby creating a sensitized-metal complex; b) adding an unsensitized chelate, and c) detecting a signal from the unsensitized chelate. The substantially non-emitting metal may be gadoliniumn and may exist in complex with a chelator. The unsensitized chelate may be terbium (Tb) or europium (Eu) and the detecting a signal may be performed by fluorescence.


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