The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2021
Filed:
Feb. 22, 2019
Applicant:
1087 Systems, Inc., Cambridge, MA (US);
Inventors:
Matthias Wagner, Cambridge, MA (US);
John Heanue, Manchester, MA (US);
Assignee:
1087 SYSTEMS, INC., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 15/14 (2006.01); G01N 15/00 (2006.01); G01N 15/10 (2006.01); B07C 5/34 (2006.01); G01N 29/24 (2006.01); G01N 21/17 (2006.01); C12N 5/071 (2010.01); B01L 3/00 (2006.01); G01N 21/3563 (2014.01); G01N 21/35 (2014.01); G01N 21/65 (2006.01);
U.S. Cl.
CPC ...
G01N 15/147 (2013.01); B01L 3/502761 (2013.01); B07C 5/34 (2013.01); C12N 5/0612 (2013.01); G01N 15/14 (2013.01); G01N 15/1427 (2013.01); G01N 15/1429 (2013.01); G01N 15/1434 (2013.01); G01N 15/1436 (2013.01); G01N 15/1459 (2013.01); G01N 15/1475 (2013.01); G01N 15/1484 (2013.01); G01N 21/1702 (2013.01); G01N 21/35 (2013.01); G01N 21/3563 (2013.01); G01N 21/65 (2013.01); G01N 29/2418 (2013.01); B01L 2200/0636 (2013.01); B01L 2200/0652 (2013.01); B01L 2300/0627 (2013.01); B01L 2300/0864 (2013.01); G01N 15/1463 (2013.01); G01N 2015/0065 (2013.01); G01N 2015/1006 (2013.01); G01N 2015/149 (2013.01); G01N 2015/1481 (2013.01); G01N 2015/1493 (2013.01); G01N 2015/1497 (2013.01); G01N 2021/653 (2013.01); G01N 2201/0612 (2013.01);
Abstract
This disclosure concerns a cytometry system including a handling system that enables presentation of single cells to at least one laser source. The laser source is configured to deliver light to a cell within the cells in order to induce bond vibrations in the cellular DNA. The system further includes a detection facility that detects the signature of the bond vibrations, wherein the bond vibration signature is used to determine the folding or packing of the DNA.