The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2021
Filed:
May. 14, 2010
Jean C. Y. Wang, Toronto, CA;
John Dick, Toronto, CA;
Jayne Danska, Toronto, CA;
Liqing Jin, Toronto, CA;
Alexandre Theocharides, Toronto, CA;
Sujeetha Rajakumar, Toronto, CA;
Jean C. Y. Wang, Toronto, CA;
John Dick, Toronto, CA;
Jayne Danska, Toronto, CA;
Liqing Jin, Toronto, CA;
Alexandre Theocharides, Toronto, CA;
Sujeetha Rajakumar, Toronto, CA;
UNIVERSITY HEALTH NETWORK, Toronto, CA;
THE HOSPITAL FOR SICK CHILDREN, Toronto, CA;
Abstract
The invention relates to modulating the SIRPα-CD47 interaction in order to treat hematological cancer and compounds therefor. In some embodiments, there is provided methods and uses of SIRPα polypeptides, fragments and fusion proteins for treating hematological cancer, preferably human acute myeloid leukemia.