The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 02, 2021

Filed:

Jun. 15, 2020
Applicants:

Yi Xiao, Miami, FL (US);

Haixiang Yu, Durham, NC (US);

Inventors:

Yi Xiao, Miami, FL (US);

Haixiang Yu, Durham, NC (US);

Attorney:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/115 (2010.01); G01N 33/94 (2006.01); G01N 21/64 (2006.01);
U.S. Cl.
CPC ...
C12N 15/115 (2013.01); G01N 21/6428 (2013.01); G01N 33/94 (2013.01); C12N 2310/16 (2013.01); C12N 2310/3517 (2013.01); G01N 2021/6434 (2013.01); G01N 2021/6439 (2013.01);
Abstract

The subject invention provides materials and methods for single-step detection of small molecules, e.g., natural and synthetic cannabinoids, in a sample. The subjection invention provides nucleic acids materials, e.g., aptamers (nucleic acid oligonucleotides) that can bind to natural and/or synthetic cannabinoids. The method for detecting a natural or synthetic cannabinoid in a sample comprises contacting the sample with an aptamer-based sensor selective for the natural or synthetic cannabinoid, and sensitively and rapidly detecting the natural or synthetic cannabinoid in the sample. The aptamer-based sensor comprises aptamers that can specifically binds to natural and/or synthetic cannabinoids with nanomolar dissociation constant.


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