The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2021
Filed:
Dec. 22, 2016
Applicants:
Board of Regents, the University of Texas System, Austin, TX (US);
Oregon State University, Corvallis, OR (US);
Inventors:
David Greenberg, Coppell, TX (US);
Bruce L. Geller, Corvallis, OR (US);
Erdal Toprak, Plano, TX (US);
Assignees:
Board of Regents, The University of Texas System, Austin, TX (US);
Oregon State University, Corvallis, OR (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 47/64 (2017.01); A61K 31/713 (2006.01); A61P 31/04 (2006.01); C07K 4/02 (2006.01); C07K 14/005 (2006.01); C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1133 (2013.01); A61K 31/713 (2013.01); A61K 47/64 (2017.08); A61P 31/04 (2018.01); C07K 4/02 (2013.01); C07K 14/005 (2013.01); C12N 9/1247 (2013.01); C12N 15/113 (2013.01); C12N 2310/11 (2013.01); C12N 2310/3233 (2013.01);
Abstract
Provided are antisense morpholino oligomers targeted against bacterial virulence factors such as genes that contribute to antibiotic resistance or biofilm formation, or essential genes, and related compositions and methods of using the oligomers and compositions, for instance, in the treatment of an infected mammalian subject.