The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2021
Filed:
Dec. 30, 2016
Centro Nacional DE Investigaciones Cardiovasculares Carlos Iii (F.s.p.), Madrid, ES;
Consejo Superior DE Investigaciones Científicas, Madrid, ES;
Universidad Autónoma DE Madrid, Madrid, ES;
Juan Miguel Redondo Moya, Madrid, ES;
Nerea Méndez-Barbero, Madrid, ES;
Jorge Oller Pedrosa, Madrid, ES;
Miguel Ramón Campanero García, Madrid, ES;
Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.), Madrid, ES;
Consejo Superior de Investigaciones Científicas, Madrid, ES;
Universidad Autónoma de Madrid, Madrid, ES;
Abstract
The present invention refers to an In vitro method for screening for subjects at risk of developing thoracic aortic aneurysm (TAA) or a disease causing TAA comprising: (a) measuring the expression pattern or level of at least A Disintegrin And Metalloproteinase with Thrombospondin Motifs 1 (ADAMTS1) obtained from an isolated biological sample of the subjects to be screened; and (b) comparing said expression pattern or level of at least ADAMTS1 of the subjects to be screened with an already established expression pattern or level, wherein reduced expression of at least ADAMTS1 is indicative of a thoracic aortic aneurysm (TAA).