The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 02, 2021

Filed:

Aug. 18, 2016
Applicants:

Riken, Wako, JP;

Kyowa Hakko Kirin Co., Ltd., Tokyo, JP;

Inventors:

Kensaku Sakamoto, Saitama, JP;

Kazumasa Ohtake, Saitama, JP;

Yoshimi Yamaguchi, Saitama, JP;

Shigeyuki Yokoyama, Saitama, JP;

Tatsuo Yanagisawa, Saitama, JP;

Akiko Matsumoto, Saitama, JP;

Akifumi Kato, Tokyo, JP;

Yasuhisa Shiraishi, Tokyo, JP;

Kaname Kimura, Tokyo, JP;

Masakazu Homma, Tokyo, JP;

Assignees:

RIKEN, Wako, JP;

KYOWA KIRIN CO., LTD., Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C07K 16/00 (2006.01); A61K 39/395 (2006.01); A61K 47/68 (2017.01); C07K 16/46 (2006.01); C07K 16/32 (2006.01); C07K 16/24 (2006.01); C07K 16/22 (2006.01); A61K 47/60 (2017.01);
U.S. Cl.
CPC ...
C07K 16/467 (2013.01); A61K 39/395 (2013.01); A61K 47/60 (2017.08); A61K 47/6803 (2017.08); A61K 47/6849 (2017.08); A61K 47/6855 (2017.08); A61K 47/6875 (2017.08); A61K 47/6889 (2017.08); C07K 16/00 (2013.01); C07K 16/22 (2013.01); C07K 16/241 (2013.01); C07K 16/28 (2013.01); C07K 16/2863 (2013.01); C07K 16/2887 (2013.01); C07K 16/32 (2013.01); C07K 16/46 (2013.01); C07K 2317/14 (2013.01); C07K 2317/20 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/33 (2013.01); C07K 2317/52 (2013.01); C07K 2317/522 (2013.01); C07K 2317/55 (2013.01); C07K 2317/71 (2013.01); C07K 2317/72 (2013.01); C07K 2317/732 (2013.01); C07K 2317/734 (2013.01); C07K 2319/30 (2013.01);
Abstract

The present invention relates to a monoclonal antibody or antibody fragment thereof as a human IgG antibody including at least one lysine derivative in a constant region of the human IgG antibody; a modified antibody or antibody fragment thereof, wherein the lysine derivative is modified; a nucleic acid including a nucleotide sequence encoding the antibody or antibody fragment thereof; a vector including the nucleic acid; a transformed cell obtained by introducing the vector into a host cell; a method for producing the antibody or antibody fragment thereof; and a composition containing the antibody or antibody fragment thereof.


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