The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 02, 2021

Filed:

Feb. 12, 2016
Applicants:

Tohoku University, Miyagi, JP;

Zenoaq Resource Co., Ltd., Fukushima, JP;

Inventors:

Yukinari Kato, Miyagi, JP;

Mika Kaneko, Miyagi, JP;

Satoshi Ogasawara, Miyagi, JP;

Assignees:

Tohoku University, Miyagi, JP;

ZENOAQ RESOURCE CO., LTD., Fukushima, JP;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); C12N 5/10 (2006.01); G01N 33/574 (2006.01); C12N 15/09 (2006.01); C07K 16/30 (2006.01); A61P 35/00 (2006.01); A61K 39/00 (2006.01); C12N 15/02 (2006.01);
U.S. Cl.
CPC ...
C07K 16/28 (2013.01); A61P 35/00 (2018.01); C07K 16/2896 (2013.01); C07K 16/30 (2013.01); C12N 5/10 (2013.01); C12N 15/02 (2013.01); C12N 15/09 (2013.01); G01N 33/574 (2013.01); G01N 33/57492 (2013.01); A61K 2039/505 (2013.01); C07K 2317/24 (2013.01); C07K 2317/41 (2013.01); C07K 2317/52 (2013.01); C07K 2317/565 (2013.01); C07K 2317/732 (2013.01); G01N 2333/705 (2013.01);
Abstract

The present invention provides a method for producing an antibody against podocalyxin expressed specifically in cancer cells. The method includes a step of introducing a nucleic acid encoding all or a portion of podocalyxin into cells expressing a cancer cell-specific sugar chain structure to cause cancer cell-specific podocalyxin or a portion thereof to be expressed therein, a step of immunizing a non-human mammal with the cancer cell-specific podocalyxin or portion thereof to obtain antibodies, and a step of purifying the antibodies by primary screening using purified cancer cell-specific podocalyxin or a portion thereof.


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