The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 02, 2021

Filed:

Jun. 17, 2016
Applicants:

National University of Singapore, Singapore, SG;

Institute of Zoology, Slovak Academy of Sciences, Bratislava, SK;

Inventors:

Janaki Krishnamoorthy Iyer, Singapore, SG;

Cho Yeow Koh, Singapore, SG;

R. Manjunatha Kini, Singapore, SG;

Maria Kazimirova, Bratislava, SK;

Ladislav Roller, Bratislava, SK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/435 (2006.01); C07K 14/81 (2006.01); A61P 7/02 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/43527 (2013.01); A61P 7/02 (2018.01); C07K 14/811 (2013.01); A61K 38/00 (2013.01);
Abstract

The present invention provides isolated peptides, variants and fragments thereof that are capable of binding with a high level of specificity to thrombin and inhibiting its activity. There is also provided uses of such peptides in methods of diagnosis and treatment, coating of medical devices and nucleic acids encoding the same.


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