The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2021
Filed:
May. 31, 2017
Applicant:
Nucana Plc, Edinburgh, GB;
Inventors:
Hugh Griffith, Edinburgh, GB;
Michaela Serpi, Cardiff, GB;
Magdalena Slusarczyk, Cardiff, GB;
Christopher McGuigan, Cardiff, GB;
Assignee:
NuCana plc, Edinburgh, GB;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07H 19/207 (2006.01); C07H 19/173 (2006.01);
U.S. Cl.
CPC ...
C07H 19/207 (2013.01); C07H 19/173 (2013.01);
Abstract
This invention relates to derivatives of cladribine of Formula (I). The compounds are phosphoramidate derivatives in which the phosphoramidate moiety is situated on the 3'-hydroxyl group of cladribine. The invention also relates to pharmaceutical formulations of the cladribine derivatives and their use in methods of treatment. The compounds are useful in the treatment of cancer.