The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 02, 2021
Filed:
Nov. 18, 2019
Applicant:
Calithera Biosciences, Inc., South San Francisco, CA (US);
Inventors:
Michael C. Van Zandt, Guilford, CT (US);
Jennifer L. Savoy, Killingworth, CT (US);
Assignee:
Calithera Biosciences, Inc., South San Francisco, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 207/16 (2006.01); C07D 207/06 (2006.01); C07C 233/05 (2006.01); C07C 233/57 (2006.01); C07B 57/00 (2006.01); C07C 233/65 (2006.01); C07C 235/06 (2006.01); C07F 5/02 (2006.01); C07C 231/12 (2006.01); C07C 327/22 (2006.01);
U.S. Cl.
CPC ...
C07D 207/16 (2013.01); C07B 57/00 (2013.01); C07C 231/12 (2013.01); C07C 233/05 (2013.01); C07C 233/57 (2013.01); C07C 233/65 (2013.01); C07C 235/06 (2013.01); C07C 327/22 (2013.01); C07D 207/06 (2013.01); C07F 5/025 (2013.01); C07B 2200/07 (2013.01); C07B 2200/13 (2013.01);
Abstract
A method is provided to conveniently separate racemic (3R,4S)-3-acetamido-4-allyl-N-(tert-butyl)pyrrolidine-3-carboxamide and (3S,4R)-3-acetamido-4-allyl-N-(tert-butyl)pyrrolidine-3-carboxamide using selective crystallization with chiral carboxylic acids.