The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 02, 2021

Filed:

Oct. 25, 2017
Applicant:

The Board of Trustees of the University of Illinois, Urbana, IL (US);

Inventors:

Rashid Bashir, Champaign, IL (US);

Ritu Raman, Champaign, IL (US);

Caroline Cvetkovic, Darien, IL (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/50 (2006.01); B25J 9/00 (2006.01); A61L 27/38 (2006.01); B25J 9/16 (2006.01); A61F 2/08 (2006.01); C12N 5/00 (2006.01); C12N 5/071 (2010.01); C12N 5/077 (2010.01); C12N 5/0793 (2010.01); G03F 7/00 (2006.01); C12N 13/00 (2006.01); A61L 27/52 (2006.01); A61F 2/02 (2006.01); A61N 1/36 (2006.01); A61N 5/06 (2006.01);
U.S. Cl.
CPC ...
B25J 9/0009 (2013.01); A61F 2/08 (2013.01); A61L 27/383 (2013.01); A61L 27/3826 (2013.01); A61L 27/3891 (2013.01); A61L 27/3895 (2013.01); A61L 27/52 (2013.01); B25J 9/1615 (2013.01); C12N 5/0062 (2013.01); C12N 5/0619 (2013.01); C12N 5/0658 (2013.01); C12N 5/0697 (2013.01); C12N 13/00 (2013.01); G01N 33/5061 (2013.01); G01N 33/5088 (2013.01); G03F 7/0037 (2013.01); A61F 2/022 (2013.01); A61F 2002/0894 (2013.01); A61F 2210/0076 (2013.01); A61N 1/36003 (2013.01); A61N 5/0622 (2013.01); C12N 2503/02 (2013.01); C12N 2503/04 (2013.01); C12N 2506/02 (2013.01); C12N 2506/1323 (2013.01); C12N 2513/00 (2013.01);
Abstract

The present disclosure provides a biological machine comprising a skeleton comprising at least one hydrogel strip and at least two hydrogel bases, and at least one bioactuator, the at least one bioactuator comprising at least one muscle ring, the muscle ring comprising skeletal muscle cells, wherein the muscle ring is tethered around the at least two pillars. The muscle ring can comprises skeletal muscle, and skeletal muscle innervated with motor neurons, allowing chemical control of muscle contraction. Methods of making the biological machine is also provided.


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