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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10905768 B1

PDFFull Text
Date of Patent:
Feb. 02, 2021

Filed:

May. 11, 2020

Heterocyclic degronimers for target protein degradation

Applicant:

C4 Therapeutics, Inc., Watertown, MA (US);

Inventors:

Andrew J. Phillips, Arlington, VA (US);

Chris G. Nasveschuk, Syoneham, MA (US);

James A. Henderson, Weston, MA (US);

Yanke Liang, Brookline, MA (US);

Mark E. Fitzgerald, Watertown, MA (US);

Minsheng He, Watertown, MA (US);

Ryan E. Michael, Newton, MA (US);

Assignee:

C4 Therapeutics, Inc., Watertown, MA (US);

Attorney:

Knowles Intellectual Property Strategies, LLC

Primary Examiner:

Mark L Shibuya

Assistant Examiner:

Ebenezer O Sackey

Int. Cl.
CPC ...
C07D 403/04 (2006.01); A61K 47/54 (2017.01); A61K 31/454 (2006.01); A61K 31/55 (2006.01); A61K 31/438 (2006.01); A61K 31/439 (2006.01); A61K 31/547 (2006.01); A61K 31/4035 (2006.01);
U.S. Cl.
CPC ...
A61K 47/545 (2017.08); A61K 31/4035 (2013.01); A61K 31/438 (2013.01); A61K 31/439 (2013.01); A61K 31/454 (2013.01); A61K 31/547 (2013.01); A61K 31/55 (2013.01); A61K 47/554 (2017.08); C07D 403/04 (2013.01);
Abstract

This invention provides heterocyclic compounds that bind to E3 Ubiquitin Ligase (typically through cereblon) ('Degrons'), which can be used as is or linked to a Targeting Ligand for a selected Target Protein for therapeutic purposes and methods of use and compositions thereof as well as methods for their preparation.

Find Patent Forward Citations

Phillips, Andrew. (2021). Heterocyclic degronimers for target protein degradation (U.S. Patent No. 10905768). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10905768

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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